Sean Yseult has played various instruments with different bands over the years, most notably her bass work with the band White Zombie. Her father, Michael S. Reynolds, was a noted biographer of Ernest Hemingway. She married Supagroup musician Chris Lee on January 12, 2008, in New Orleans, Louisiana, where she lives. She once owned and ran a dive bar popular among artists and musicians, The Saint, in that city's Garden District, however sold it within the last year.
Yseult played bass in White Zombie for 11 years before they disbanded in 1998. In 1996, she participated along with Jay Yuenger in the tribute band to The Germs called Ruined Eye. After the breakup of White Zombie in September 1998, Yseult started playing bass for the band Rock City Morgue. She formed the Famous Monsters in 1995 which also featured Katie Lynn Campbell, bassist for the Toronto based C'mon. She plays bass in the band, Star & Dagger, which recorded an album at a studio in Joshua Tree, which was released in 2012.
On November 1, 2010, Yseult released Iâm in the Band, a book containing tour diaries and photos as well as detailing her eleven years spent as a member of White Zombie.
When Rock N Roll Experience Magazine asked Yseult in 2011 why she was not involved in the White Zombie Box set her reply was, "It was a little bit of a fuck you to me & J. which was kinda weird since we were 2/3rd's of the band but anyways.â